Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus

Systemic lupus erythematosus (SLE) is a severe autoimmune disease that is associated with increased circulating apoptotic cell autoantigens (AC-Ags) as well as increased type I IFN signaling. Here, we describe a pathogenic mechanism in which follicular translocation of marginal zone (MZ) B cells in...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Li, Hao, Fu, Yang-Xin, Wu, Qi, Zhou, Yong, Crossman, David K., Yang, PingAr, Li, Jun, Luo, Bao, Morel, Laurence M., Kabarowski, Janusz H., Yagita, Hideo, Ware, Carl F., Hsu, Hui-Chen, Mountz, John D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563689/
https://ncbi.nlm.nih.gov/pubmed/26098211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81059
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