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Discovery of a series of novel phenylpiperazine derivatives as EGFR TK inhibitors
Human epidermal growth factor receptor (EGFR) is an important drug target that plays a fundamental role in signal transduction pathways in oncology. We report herein the discovery of a novel class of phenylpiperazine derivatives with improved potency toward EGFR. The biological activity of compound...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563558/ https://ncbi.nlm.nih.gov/pubmed/26349898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13934 |
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