Potentiation of cGMP signaling increases oxygen delivery and oxidative metabolism in contracting skeletal muscle of older but not young humans

Aging is associated with progressive loss of cardiovascular and skeletal muscle function. The impairment in physical capacity with advancing age could be related to an insufficient peripheral O(2) delivery to the exercising muscles. Furthermore, the mechanisms underlying an impaired blood flow regul...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Nyberg, Michael, Piil, Peter, Egelund, Jon, Sprague, Randy S, Mortensen, Stefan P, Hellsten, Ylva
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562591/
https://ncbi.nlm.nih.gov/pubmed/26272735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12508
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