APOL1 kidney disease risk variants – an evolving landscape

APOL1 genetic variants account for much of the excess risk of chronic and end stage kidney disease, which results in a significant global health disparity for persons of African ancestry. We estimate the lifetime risk of kidney disease in APOL1 dual-risk allele individuals to be at least 15%. Experi...

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Bibliographic Details
Published in:Semin Nephrol
Main Authors: Dummer, Patrick D., Limou, Sophie, Rosenberg, Avi Z., Heymann, Jurgen, Nelson, George, Winkler, Cheryl A., Kopp, Jeffrey B.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562465/
https://ncbi.nlm.nih.gov/pubmed/26215860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2015.04.008
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