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APOL1 Kidney Risk Alleles: Population Genetics and Disease Associations
APOL1 kidney disease is a unique case in the field of the genetics of common disease: 2 variants (termed G1 and G2) with high population frequency have been repeatedly associated with nondiabetic CKDs, with very strong effect size (odds ratios 3–29) in populations of sub-Saharan African descent. Thi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157456/ https://ncbi.nlm.nih.gov/pubmed/25168832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ackd.2014.06.005 |
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