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DNA polymerase eta is regulated by poly(rC)-binding protein 1 via mRNA stability
DNA polymerase eta (POLH), a target of p53 tumor suppressor, plays a key role in translesion DNA synthesis (TLS). Loss of POLH is responsible for human cancer prone syndrome, Xeroderma Pigmentosum Variant (XPV). Due to its critical role in DNA repair and genome stability, POLH expression and activit...
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| 發表在: | Biochem J |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562393/ https://ncbi.nlm.nih.gov/pubmed/25268038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141164 |
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