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Structural and Thermodynamic Characteristics of Amyloidogenic Intermediates of β-2-Microglobulin

β-2-microglobulin (β2m) self-aggregates to form amyloid fibril in renal patients taking long-term dialysis treatment. Despite the extensive structural and mutation studies carried out so far, the molecular details on the factors that dictate amyloidogenic potential of β2m remain elusive. Here we rep...

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Publicat a:Sci Rep
Autors principals: Chong, Song-Ho, Hong, Jooyeon, Lim, Sulgi, Cho, Sunhee, Lee, Jinkeong, Ham, Sihyun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562173/
https://ncbi.nlm.nih.gov/pubmed/26348154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13631
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