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Structural and Thermodynamic Characteristics of Amyloidogenic Intermediates of β-2-Microglobulin

β-2-microglobulin (β2m) self-aggregates to form amyloid fibril in renal patients taking long-term dialysis treatment. Despite the extensive structural and mutation studies carried out so far, the molecular details on the factors that dictate amyloidogenic potential of β2m remain elusive. Here we rep...

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書目詳細資料
發表在:Sci Rep
Main Authors: Chong, Song-Ho, Hong, Jooyeon, Lim, Sulgi, Cho, Sunhee, Lee, Jinkeong, Ham, Sihyun
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562173/
https://ncbi.nlm.nih.gov/pubmed/26348154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13631
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