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Graphic Mining of High-Order Drug Interactions and Their Directional Effects on Myopathy Using Electronic Medical Records

We propose to study a novel pharmacovigilance problem for mining directional effects of high-order drug interactions on an adverse drug event (ADE). Our goal is to estimate each individual risk of adding a new drug to an existing drug combination. In this proof-of-concept study, we analyzed a large...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Du, L, Chakraborty, A, Chiang, C-W, Cheng, L, Quinney, SK, Wu, H, Zhang, P, Li, L, Shen, L
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562164/
https://ncbi.nlm.nih.gov/pubmed/26380157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.59
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