A Mixture Dose–Response Model for Identifying High-Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases

Interactions between multiple drugs may yield excessive risk of adverse effects. This increased risk is not uniform for all combinations, although some combinations may have constant adverse effect risks. We developed a statistical model using medical record data to identify drug combinations that i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:CPT Pharmacometrics Syst Pharmacol
Egile Nagusiak: Zhang, P, Du, L, Wang, L, Liu, M, Cheng, L, Chiang, C-W, Wu, H-Y, Quinney, SK, Shen, L, Li, L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2015
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562163/
https://ncbi.nlm.nih.gov/pubmed/26380156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.53
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