Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G(2)/M cell cycle arrest and DNA damage

AIM: Cathepsin L is a lysosomal cysteine protease that plays important roles in cancer tumorigenesis, proliferation and chemotherapy resistance. The aim of this study was to determine how cathepsin L regulated the radiosensitivity of human glioma cells in vitro. METHODS: Human glioma U251 cells (har...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Acta Pharmacol Sin
मुख्य लेखकों: Zhang, Qing-qing, Wang, Wen-juan, Li, Jun, Yang, Neng, Chen, Gang, Wang, Zhong, Liang, Zhong-qin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2015
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561966/
https://ncbi.nlm.nih.gov/pubmed/26095040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.36
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