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A Complex Signaling Cascade Governs Pristinamycin Biosynthesis in Streptomyces pristinaespiralis

Pristinamycin production in Streptomyces pristinaespiralis Pr11 is tightly regulated by an interplay between different repressors and activators. A γ-butyrolactone receptor gene (spbR), two TetR repressor genes (papR3 and papR5), three SARP (Streptomyces antibiotic regulatory protein) genes (papR1,...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Mast, Yvonne, Guezguez, Jamil, Handel, Franziska, Schinko, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561715/
https://ncbi.nlm.nih.gov/pubmed/26187956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00728-15
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