Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors

MicroRNAs regulate eukaryotic gene expression upon pairing onto target mRNAs. This targeting is influenced by the complementarity between the microRNA “seed” sequence at its 5′ end and the seed-matching sequences in the mRNA. Here, we assess the efficiency and specificity of 8-mer locked nucleic aci...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther Nucleic Acids
मुख्य लेखकों: Staedel, Cathy, Varon, Christine, Nguyen, Phu Hung, Vialet, Brune, Chambonnier, Lucie, Rousseau, Benoît, Soubeyran, Isabelle, Evrard, Serge, Couillaud, Franck, Darfeuille, Fabien
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2015
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561653/
https://ncbi.nlm.nih.gov/pubmed/26151747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.18
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