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Discriminating somatic and germline mutations in tumor DNA samples without matching normals
Tumor analyses commonly employ a correction with a matched normal (MN), a sample from healthy tissue of the same individual, in order to distinguish germline mutations from somatic mutations. Since the majority of variants found in an individual are thought to be common within the population, we con...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561496/ https://ncbi.nlm.nih.gov/pubmed/26209359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.183053.114 |
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