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Sequential replication-coupled destruction at G1/S ensures genome stability
Timely ubiquitin-mediated protein degradation is fundamental to cell cycle control, but the precise degradation order at each cell cycle phase transition is still unclear. We investigated the degradation order among substrates of a single human E3 ubiquitin ligase, CRL4(Cdt2), which mediates the S-p...
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| 發表在: | Genes Dev |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561482/ https://ncbi.nlm.nih.gov/pubmed/26272819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263731.115 |
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