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Noninvasive Prenatal Screening for Genetic Diseases Using Massively Parallel Sequencing of Maternal Plasma DNA

The identification of cell-free fetal DNA (cffDNA) in maternal plasma in 1997 heralded the most significant change in obstetric care for decades, with the advent of safer screening and diagnosis based on analysis of maternal blood. Here, we describe how the technological advances offered by next-gen...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Chitty, Lyn S., Lo, Y. M. Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561399/
https://ncbi.nlm.nih.gov/pubmed/26187875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023085
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