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B Cell-Specific MHC Class II Deletion Reveals Multiple Non-Redundant Roles for B Cell Antigen Presentation in Murine Lupus()

B cells have both antibody-dependent and antibody-independent functions in systemic autoimmune diseases, including systemic lupus erythematosus (SLE). Antibody-independent functions are known to be important, since mice with B cells but no secreted immunoglobulin have severe disease. These functions...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Giles, Josephine R., Kashgarian, Michael, Koni, Pandelakis A., Shlomchik, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561209/
https://ncbi.nlm.nih.gov/pubmed/26268653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500792
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