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T-helper cell diversity in experimental autoimmune encephalomyelitis and Multiple Sclerosis

Multiple sclerosis (MS) is believed to be initiated by myelin-reactive CD4(+) Th cells. IL-12 polarized Th1 cells, IL-23 polarized Th17 cells, and exTh17 cells (Th17 cells that acquire Th1 characteristics) have each been implicated in autoimmune pathogenesis. It is currently debated whether Th cells...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Carbajal, Kevin S., Mironova, Yevgeniya, Ulrich-Lewis, Justin T., Kulkarni, Deven, Grifka-Walk, Heather M., Huber, Amanda K., Shrager, Peter, Giger, Roman J., Segal, Benjamin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561206/
https://ncbi.nlm.nih.gov/pubmed/26238492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501097
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