Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis

Autoreactive CD4(+) T lymphocytes play a vital role in the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Since the discovery of T helper 17 cells, there is an ongoing debate whether T helper 1, T helper 17 or both subtypes of T lymphocytes are im...

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Detalhes bibliográficos
Main Authors: Kleiter, Ingo, Song, Jian, Lukas, Dominika, Hasan, Maruf, Neumann, Bernhard, Croxford, Andrew L., Pedré, Xiomara, Hövelmeyer, Nadine, Yogev, Nir, Mildner, Alexander, Prinz, Marco, Wiese, Elena, Reifenberg, Kurt, Bittner, Stefan, Wiendl, Heinz, Steinman, Lawrence, Becker, Christoph, Bogdahn, Ulrich, Neurath, Markus F., Steinbrecher, Andreas, Waisman, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850583/
https://ncbi.nlm.nih.gov/pubmed/20354004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq039
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