Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis

Autoreactive CD4(+) T lymphocytes play a vital role in the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Since the discovery of T helper 17 cells, there is an ongoing debate whether T helper 1, T helper 17 or both subtypes of T lymphocytes are im...

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Main Authors: Kleiter, Ingo, Song, Jian, Lukas, Dominika, Hasan, Maruf, Neumann, Bernhard, Croxford, Andrew L., Pedré, Xiomara, Hövelmeyer, Nadine, Yogev, Nir, Mildner, Alexander, Prinz, Marco, Wiese, Elena, Reifenberg, Kurt, Bittner, Stefan, Wiendl, Heinz, Steinman, Lawrence, Becker, Christoph, Bogdahn, Ulrich, Neurath, Markus F., Steinbrecher, Andreas, Waisman, Ari
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
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Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850583/
https://ncbi.nlm.nih.gov/pubmed/20354004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq039
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