Systemic Exposure to Thiopurines and Risk of Relapse in Children with Acute Lymphoblastic Leukemia: A Children’s Oncology Group Study

IMPORTANCE: Variability in prescribed 6-mercaptopurine and lack of adherence to 6-mercaptopurine could result in intra-individual variability in systemic exposure to 6-mercaptopurine (measured as erythrocyte thioguanine nucleotide levels) in children with acute lymphoblastic leukemia. The impact of...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Bhatia, Smita, Landier, Wendy, Hageman, Lindsey, Chen, Yanjun, Kim, Heeyoung, Sun, Can-Lan, Kornegay, Nancy, Evans, William E, Angiolillo, Anne L, Bostrom, Bruce, Casillas, Jacqueline, Lew, Glen, Maloney, Kelly W, Mascarenhas, Leo, Ritchey, A. Kim, Termuhlen, Amanda M, Carroll, William L, Wong, F Lennie, Relling, Mary V
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561178/
https://ncbi.nlm.nih.gov/pubmed/26181173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.0245
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