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X Inactivation Lessons from Differentiating Mouse Embryonic Stem Cells

X chromosome inactivation (XCI) is the dosage compensation mechanism that evolved in female mammals to correct the genetic imbalance of X-linked genes between sexes. X chromosome inactivation occurs in early development when one of the two X chromosomes of females is nearly-completely silenced. Diff...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev
Main Authors: Pintacuda, Greta, Cerase, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561061/
https://ncbi.nlm.nih.gov/pubmed/26198263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-015-9597-5
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