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Label-Free DNA Sequencing Using Millikan Detection

A label-free method for DNA sequencing based on the principle of the Millikan oil drop experiment was developed. This sequencing-by-synthesis approach sensed increases in bead charge as nucleotides were added by a polymerase to DNA templates attached to beads. The balance between an electrical force...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Dettloff, Roger, Leiske, Danielle, Chow, Andrea, Farinas, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560655/
https://ncbi.nlm.nih.gov/pubmed/26151683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.06.036
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