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Label-free Detection for a DNA Methylation Assay Using Raman Spectroscopy

BACKGROUND: DNA methylation has been suggested as a biomarker for early cancer detection and treatment. Varieties of technologies for detecting DNA methylation have been developed, but they are not sufficiently sensitive for use in diagnostic devices. The aim of this study was to determine the suita...

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Bibliographic Details
Published in:Chin Med J (Engl)
Main Authors: Kim, Jeongho, Park, Hae Jeong, Kim, Jae Hyung, Chang, Boksoon, Park, Hun-Kuk
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555131/
https://ncbi.nlm.nih.gov/pubmed/28776549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.211874
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