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Metabolic Adaptation Processes That Converge to Optimal Biomass Flux Distributions

In simple organisms like E.coli, the metabolic response to an external perturbation passes through a transient phase in which the activation of a number of latent pathways can guarantee survival at the expenses of growth. Growth is gradually recovered as the organism adapts to the new condition. Thi...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Altafini, Claudio, Facchetti, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560427/
https://ncbi.nlm.nih.gov/pubmed/26340476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004434
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