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Partial inhibition and bilevel optimization in flux balance analysis

MOTIVATION: Within Flux Balance Analysis, the investigation of complex subtasks, such as finding the optimal perturbation of the network or finding an optimal combination of drugs, often requires to set up a bilevel optimization problem. In order to keep the linearity and convexity of these nested o...

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書目詳細資料
發表在:BMC Bioinformatics
Main Authors: Facchetti, Giuseppe, Altafini, Claudio
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219332/
https://ncbi.nlm.nih.gov/pubmed/24286232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-344
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