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Partial inhibition and bilevel optimization in flux balance analysis

MOTIVATION: Within Flux Balance Analysis, the investigation of complex subtasks, such as finding the optimal perturbation of the network or finding an optimal combination of drugs, often requires to set up a bilevel optimization problem. In order to keep the linearity and convexity of these nested o...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Facchetti, Giuseppe, Altafini, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219332/
https://ncbi.nlm.nih.gov/pubmed/24286232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-344
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