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Pivotal role of amino acid at position 138 in the allosteric hinge reorientation of cAMP receptor protein.
The cAMP receptor protein (CRP) of Escherichia coli needs cAMP for an allosteric change to regulate gene expression by binding to specific DNA sites. The hinge region connecting the DNA-binding domain to the cAMP-binding domain has been proposed to participate in the cAMP-induced allosteric change n...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
1993
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC45602/ https://ncbi.nlm.nih.gov/pubmed/8380500 |
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