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Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis
BACKGROUND: Targeting CTLA-4 is a recent strategic approach in cancer control: blocking CTLA-4 enhances an antitumor immunity by promoting T-cell activation and cytotoxic T-lymphocyte proliferation. This induction of a tolerance break against the tumor may be responsible for immune-related adverse e...
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| 出版年: | BMC Med |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4559965/ https://ncbi.nlm.nih.gov/pubmed/26337719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0455-8 |
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