Ipilimumab and immune-mediated adverse events: a case report of anti-CTLA4 induced ileitis

BACKGROUND: Ipilimumab is a fully human monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 , a key negative regulator of T-cell activation approved by the Food and Drug Administration as of March 2011 for the treatment of metastatic melanoma. As a result of the up-regulation of th...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Venditti, Olga, De Lisi, Delia, Caricato, Marco, Caputo, Damiano, Capolupo, Gabriella Teresa, Taffon, Chiara, Pagliara, Elisa, Battisi, Sofia, Frezza, Anna Maria, Onetti Muda, Andrea, Tonini, Giuseppe, Santini, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350587/
https://ncbi.nlm.nih.gov/pubmed/25885696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1074-7
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