A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation

BACKGROUND: A converging body of evidence indicates that levels of adult hippocampal neurogenesis vary along the septo-temporal axis of the dentate gyrus, but the molecular mechanisms underlying this regional heterogeneity are not known. We previously identified a niche mechanism regulating prolifer...

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Vydáno v:Mol Brain
Hlavní autoři: Sun, Jiaqi, Bonaguidi, Michael A., Jun, Heechul, Guo, Junjie U., Sun, Gerald J., Will, Brett, Yang, Zhengang, Jang, Mi-Hyeon, Song, Hongjun, Ming, Guo-li, Christian, Kimberly M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559945/
https://ncbi.nlm.nih.gov/pubmed/26337530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0143-9
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