A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation

BACKGROUND: A converging body of evidence indicates that levels of adult hippocampal neurogenesis vary along the septo-temporal axis of the dentate gyrus, but the molecular mechanisms underlying this regional heterogeneity are not known. We previously identified a niche mechanism regulating prolifer...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Sun, Jiaqi, Bonaguidi, Michael A., Jun, Heechul, Guo, Junjie U., Sun, Gerald J., Will, Brett, Yang, Zhengang, Jang, Mi-Hyeon, Song, Hongjun, Ming, Guo-li, Christian, Kimberly M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559945/
https://ncbi.nlm.nih.gov/pubmed/26337530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0143-9
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