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Molecular insights into Substrate Specificity of Prostate Specific Antigen through Structural Modeling

Prostate Specific Antigen’s (PSA) role as a biomarker for prostate cancer is well established but the physiological role of its serine protease activity in the pathobiology of normal prostate and prostate carcinogenesis remains largely unknown. In light of recent studies that implicate PSA’s enzymat...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Singh, Pratap, LeBeau, Aaron M., Lilja, Hans, Denmeade, Samuel R., Isaacs, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559854/
https://ncbi.nlm.nih.gov/pubmed/19705489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22524
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