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Molecular insights into Substrate Specificity of Prostate Specific Antigen through Structural Modeling

Prostate Specific Antigen’s (PSA) role as a biomarker for prostate cancer is well established but the physiological role of its serine protease activity in the pathobiology of normal prostate and prostate carcinogenesis remains largely unknown. In light of recent studies that implicate PSA’s enzymat...

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Dettagli Bibliografici
Pubblicato in:Proteins
Autori principali: Singh, Pratap, LeBeau, Aaron M., Lilja, Hans, Denmeade, Samuel R., Isaacs, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559854/
https://ncbi.nlm.nih.gov/pubmed/19705489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22524
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