Polarisation of Tumor-Associated Macrophages toward M2 Phenotype Correlates with Poor Response to Chemoradiation and Reduced Survival in Patients with Locally Advanced Cervical Cancer

OBJECTIVE: we investigate the prognostic role of pre-treatment ratio between Type 1 (M1) and Type 2 (M2) tumor-associated macrophages (TAMs) in locally advanced cervical cancer (LACC) patients treated with chemoradiation (CT/RT). METHODS: 84 consecutive LACC patients treated with cisplatin-based CT/...

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Udgivet i:PLoS One
Main Authors: Petrillo, Marco, Zannoni, Gian Franco, Martinelli, Enrica, Pedone Anchora, Luigi, Ferrandina, Gabriella, Tropeano, Giovanna, Fagotti, Anna, Scambia, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559430/
https://ncbi.nlm.nih.gov/pubmed/26335330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136654
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