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Slit-Dependent Endocytic Trafficking of the Robo Receptor Is Required for Son of Sevenless Recruitment and Midline Axon Repulsion

Understanding how axon guidance receptors are activated by their extracellular ligands to regulate growth cone motility is critical to learning how proper wiring is established during development. Roundabout (Robo) is one such guidance receptor that mediates repulsion from its ligand Slit in both in...

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Vydáno v:PLoS Genet
Hlavní autoři: Chance, Rebecca K., Bashaw, Greg J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559387/
https://ncbi.nlm.nih.gov/pubmed/26335920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005402
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