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Resistance to thyroid hormone due to defective thyroid receptor alpha

Thyroid hormones act via nuclear receptors (TRα1, TRβ1, TRβ2) with differing tissue distribution; the role of α2 protein, derived from the same gene locus as TRα1, is unclear. Resistance to thyroid hormone alpha (RTHα) is characterised by tissue-specific hypothyroidism associated with near-normal th...

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Detalhes bibliográficos
Publicado no:Best Pract Res Clin Endocrinol Metab
Main Authors: Moran, Carla, Chatterjee, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
11
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559105/
https://ncbi.nlm.nih.gov/pubmed/26303090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beem.2015.07.007
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