Isoniazid-induced polyneuropathy in a tuberculosis patient – implication for individual risk stratification with genotyping?

BACKGROUND: Development of polyneuropathy (PNP) under treatment for tuberculosis (TB), including isoniazid (INH), is a highly relevant adverse drug effect. The NAT2 acetylation status is a predictor of potential toxic effects of INH. The question as to whether individual risk stratification by genot...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Stettner, Mark, Steinberger, Daniela, Hartmann, Christian J, Pabst, Tatjana, Konta, Lidija, Hartung, Hans Peter, Kieseier, Bernd C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559012/
https://ncbi.nlm.nih.gov/pubmed/26355945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.326
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