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Enantioselective Synthesis of Carbo- and Heterocycles through a CuH-Catalyzed Hydroalkylation Approach

[Image: see text] The enantioselective, intramolecular hydroalkylation of halide-tethered styrenes has been achieved through a copper hydride-catalyzed process. This approach allowed for the synthesis of enantioenriched cyclobutanes, cyclopentanes, indanes, and six-membered N- and O-heterocycles. Th...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Wang, Yi-Ming, Bruno, Nicholas C., Placeres, Ángel L., Zhu, Shaolin, Buchwald, Stephen L.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2015
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558994/
https://ncbi.nlm.nih.gov/pubmed/26256576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07061
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