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The Evolution of Bony Vertebrate Enhancers at Odds with Their Coding Sequence Landscape

Enhancers lie at the heart of transcriptional and developmental gene regulation. Therefore, changes in enhancer sequences usually disrupt the target gene expression and result in disease phenotypes. Despite the well-established role of enhancers in development and disease, evolutionary sequence stud...

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Detalles Bibliográficos
Publicado en:Genome Biol Evol
Main Authors: Yousaf, Aisha, Sohail Raza, Muhammad, Ali Abbasi, Amir
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558863/
https://ncbi.nlm.nih.gov/pubmed/26253316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv146
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