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Evolution and Functional Diversification of the GLI Family of Transcription Factors in Vertebrates

BACKGROUND: In vertebrates the “SONIC HEDGEHOG” signalling pathway has been implicated in cell-fate determination, proliferation and the patterning of many different cell types and organs. As the GLI family members (GLI1, GLI2 and GLI3) are key mediators of hedgehog morphogenetic signals, over the p...

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Detalhes bibliográficos
Main Authors: Abbasi, Amir Ali, Goode, Debbie K., Amir, Saneela, Grzeschik, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747127/
https://ncbi.nlm.nih.gov/pubmed/19812723
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