CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injury

Ischemia-reperfusion occurs in a great many clinical settings and contributes to organ failure or dysfunction. CD154-CD40 signaling in leukocyte–endothelial cell interactions or T-cell activation facilitates tissue inflammation and injury. Here we tested a siRNA anti-CD40 in rodent warm and cold isc...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: de Ramon, Laura, Ripoll, Elia, Merino, Ana, Lúcia, Marc, Aran, Josep M, Pérez-Rentero, S, Lloberas, Nuria, Cruzado, Josep M, Grinyó, Josep M, Torras, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558568/
https://ncbi.nlm.nih.gov/pubmed/25993320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.146
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