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CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injury
Ischemia-reperfusion occurs in a great many clinical settings and contributes to organ failure or dysfunction. CD154-CD40 signaling in leukocyte–endothelial cell interactions or T-cell activation facilitates tissue inflammation and injury. Here we tested a siRNA anti-CD40 in rodent warm and cold isc...
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| Veröffentlicht in: | Kidney Int |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558568/ https://ncbi.nlm.nih.gov/pubmed/25993320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.146 |
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