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DED or alive: assembly and regulation of the death effector domain complexes

Death effector domains (DEDs) are protein–protein interaction domains initially identified in proteins such as FADD, FLIP and caspase-8 involved in regulating apoptosis. Subsequently, these proteins have been shown to have important roles in regulating other forms of cell death, including necroptosi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Riley, J S, Malik, A, Holohan, C, Longley, D B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558505/
https://ncbi.nlm.nih.gov/pubmed/26313917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.213
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