Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson's disease

Parkinson's disease (PD) is an age-related progressive neurodegenerative disease associated with selective loss of dopaminergic neurons. The characteristic hallmark of the disease is intracytoplasmic proteinacious inclusion bodies called Lewy bodies, primarily consisting of a presynaptic protei...

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Vydáno v:Exp Mol Med
Hlavní autoři: Basu, Sambuddha, Je, Goun, Kim, Yoon-Seong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558488/
https://ncbi.nlm.nih.gov/pubmed/26315598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.54
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