Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy

The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus, the elucidation of mechanisms of resistance is urgently needed. The crucial functions of Activating Transcription Factor-2 (ATF2) in the development and therapeutic resi...

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Publicado no:Oncogene
Main Authors: Lau, Eric, Sedy, John, Sander, Cindy, Shaw, Misa Austin, Feng, Yongmei, Scortegagna, Marzia, Claps, Giuseppina, Robinson, Steven, Cheng, Phil, Srivas, Rohith, Soonthornvacharin, Stephen, Ideker, Trey, Bosenberg, Marcus, Gonzalez, Réné, Robinson, William, Chanda, Sumit, Ware, Carl, Dummer, Reinhard, Hoon, Dave, Kirkwood, John M., Ronai, Ze'ev A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558399/
https://ncbi.nlm.nih.gov/pubmed/25728676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.22
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