Androgen receptor splice variants dimerize to transactivate target genes

Constitutively-active androgen receptor splice variants (AR-V) lacking the ligand-binding domain have been implicated in the pathogenesis of castration-resistant prostate cancer and in mediating resistance to newer drugs that target the androgen axis. AR-V regulate expression of both canonical AR ta...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Xu, Duo, Zhan, Yang, Qi, Yanfeng, Cao, Bo, Bai, Shanshan, Xu, Wei, Gambhir, Sanjiv S., Lee, Peng, Sartor, Oliver, Flemington, Erik K., Zhang, Haitao, Hu, Chang-Deng, Dong, Yan
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558376/
https://ncbi.nlm.nih.gov/pubmed/26060018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0381
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