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Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy
Upregulation of androgen receptor splice variants (AR-Vs), especially AR-V7, is associated with castration resistance of prostate cancer. At the RNA level, AR-V7 upregulation is generally coupled with increased full-length AR (AR-FL); consequently, AR-V7 and AR-Vs collectively constitute a minority...
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| Publicado no: | Cancer Lett |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7940584/ https://ncbi.nlm.nih.gov/pubmed/33556543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.12.037 |
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