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Target-specific variants of Flp recombinase mediate genome engineering reactions in mammalian cells
Genome engineering relies on DNA modifying enzymes that are able to locate a DNA sequence of interest and initiate a desired genome rearrangement. Currently, the field predominantly utilizes site-specific DNA nucleases that depend on the host DNA repair machinery to complete a genome modification ta...
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| Veröffentlicht in: | FEBS J |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558331/ https://ncbi.nlm.nih.gov/pubmed/26077105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13345 |
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