GABRA2 alcohol dependence risk allele is associated with reduced expression of chromosome 4p12 GABA(A) subunit genes in human neural cultures

BACKGROUND: Genetic variation in a region of chromosome 4p12 that includes the GABA(A)-subunit gene GABRA2 has been reproducibly associated with alcohol dependence (AD). However, the molecular mechanisms underlying the association are unknown. This study examined correlates of in vitro gene expressi...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Lieberman, Richard, Kranzler, Henry R., Joshi, Pujan, Shin, Dong-Guk, Covault, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558268/
https://ncbi.nlm.nih.gov/pubmed/26250693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12807
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