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GABRA2 alcohol dependence risk allele is associated with reduced expression of chromosome 4p12 GABA(A) subunit genes in human neural cultures

BACKGROUND: Genetic variation in a region of chromosome 4p12 that includes the GABA(A)-subunit gene GABRA2 has been reproducibly associated with alcohol dependence (AD). However, the molecular mechanisms underlying the association are unknown. This study examined correlates of in vitro gene expressi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Alcohol Clin Exp Res
Egile Nagusiak: Lieberman, Richard, Kranzler, Henry R., Joshi, Pujan, Shin, Dong-Guk, Covault, Jonathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558268/
https://ncbi.nlm.nih.gov/pubmed/26250693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12807
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