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Measurement of the Entrainment Window of Islets of Langerhans by Microfluidic Delivery of a Chirped Glucose Waveform

Within single islets of Langerhans, the endocrine portion of the pancreas, intracellular metabolites, as well as insulin secretion, oscillates with a period of ~5 min. In vivo, pulsatile insulin oscillations are also observed with periods ranging from 5 – 15 minutes. In order for oscillations of ins...

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Publicat a:Integr Biol (Camb)
Autors principals: Dhumpa, Raghuram, Truong, Tuan M., Wang, Xue, Roper, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558223/
https://ncbi.nlm.nih.gov/pubmed/26211670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00156k
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